Curculigoside (1-64 μg/ml; 72 hours) exerts significant inhibitory effects on MH7A cell viability between 1 and 64 µg/ml in MH7A cells.
Curculigoside (4-16 μg/ml; 24 hours) decreases the protein expression of JAK1, JAK3 and STAT3 compared to the TNF-α group.
Cell Viability Assay
Cell Line:
MH7A cells
Concentration:
1 μg/ml; 2 μg/ml; 4 μg/ml; 8 μg/ml; 16 μg/ml; 32 μg/ml; 64 μg/ml
Incubation Time:
72 hours
Result:
Had inhibitory effect on MH7A cells.
Western Blot Analysis
Cell Line:
MH7A cells
Concentration:
4 μg/ml; 64 μg/ml
Incubation Time:
24 hours
Result:
Downregulated JAK1, JAK3 and STAT3 protein expression.